Jmcgh and Other sites: Non-Urine Sites Only

 Numbers are percent susceptible

Gram Negative

 Organisms

No. of

isolates

amk

am/s

cz

fep

caz

cx

esbl

(+)

etp

gm

le

mer

pip/

taz

tmp/

smx

Acinetobacter

baumannii

68

-

84

-

46

29

-

-

-

74

38

93

-

41

Citrobacter

freundii

11*

100

-

0

100

91

91

-

100

82

82

100

-

73

Citrobacter

koseri

13*

100

-

92

100

92

100

-

100

100

77

100

-

77

Enterobacter

aerogenes

17*

100

-

0

100

100

100

-

100

100

100

100

94

100

Enterobacter

cloacae

77

100

-

0

95

74

77

-

91

90

86

100

79

90

Escherichia

coli

285

100

43

84

92

90

90

8

100

81

51

100

94

63

Klebsiella

oxytoca

27*

100

85

70

100

100

100

0

100

100

100

100

100

100

Klebsiella

pneumoniae

104

100

84

92

92

92

92

8

100

98

91

100

98

96

Morganella

morganii

29*

100

0

0

97

79

100

-

100

86

59

100

90

52

Proteus

 mirabilis

245

100

65

92

97

96

96

-

99

81

38

100

99

39

Providencia stuartii

25*

100

0

0

96

100

100

-

-

52

20

100

88

56

Pseudomonas

aeruginosa

311

98

-

-

77

81

-

-

-

83

58

82

85

-

Serratia

marcescens

37

100

-

0

100

100

100

-

100

100

97

100

100

97

Stenotrophomonas maltophilia

43/24(le)*

-

-

-

-

-

-

-

-

 

75

-

-

91

 

*NO. of isolates-“Percent susceptible for each organism/antimicrobial combination was generated by including the first isolate of that organism recovered from a given patient.” When fewer that 30 isolates are reported it should be noted that less than statistical validity of the estimates of percent susceptibility exist.

 

Abbreviation Key: amk- amikacin, am/s-ampicillin/sulbactam, cz-cefazolin, fep- cefepime, caz-ceftazidime,

cx-ceftriaxone, esbl-Extended Spectrum Beta Lactamase, etp-ertapenem, gm-gentamicin, le-levofloxacin,

mer-Meropenem nit-nitrofurantoin, pip/taz-piperacillin/tazobactam, tmp/smx-trimethoprim/sulfa

 

- antibiotics not tested or not recommended due to lack of correlation between in vitro results and in vivo activity.

 

Comments:

·          71% of Haemophilus infuenzae isolates were beta lactamase negative (95 isolates tested). Beta Lactamase negative indicates probable susceptibility to penicillin, ampicillin and 1st generation cephalosporins. Beta lactamase positive indicates probable resistance to ampicillin, amoxicillin and first generation cephalosporins. Recommended therapy is combination therapy or a third generation cephalosporin.

·          88% of Moraxella (Branhamella) catarrhalis were beta lactamase positive (26 isolates tested). Beta lactamase positive indicates resistance to penicillin, ampicillin and first generation cephalosporins. Several beta-lactams are effective including beta lactam/Beta Lactamase inhibitory combinations, 3rd generation cephalosporins, macrolides, quinolones and trimethoprim/sulfamethoxazole.

·          38 isolates of Salmonella species and 5 Shigella species were recovered. Susceptibility testing is not routinely performed on intestinal sites. Extraintestinal sites are tested against ampicillin, trimethoprim/sulfa and a third generation cephalosporin. Intestinal source isolates will be tested per telephone request.

·          5 Campylobacter species were isolated in 2009.

·          3 Giardia lamblia positive rapid antigens were confirmed in 2009.

·          1 Cryptosporidium positive rapid antigens were confirmed in 2009.