Jmcgh and Other Sites: Non-Urine Sites Only

                                                             Numbers are percent susceptible, “()”Numbers are percent intermediate

Gram Positive Organsims

No. of isoaltes

am

cx

*m

cx

*nm

cc

dap

e

gm

le

lnz

ox

rif

te

tmp/

smx

van

Coagulase Negative Staph

1295

-

-

-

56

-

32

78

42

100

26

94

71

-

100

Enterococcus Species

473

85

-

-

-

-

16

-

-

96

-

 

27

-

83

Staphylococcus aureus

1622

-

-

-

66

100

28

94

59

100

33

99

91

97

100

Streptococcus pneumoniae

56

-

79

96

-

-

33

-

100

100

-

 

67

60

100

Abbreviation Key: am-ampicillin, cx-ceftriaxone, CC-clindamycin, e-erythromycin, gm-gentamicin, le-levofloxacin, lnz-linezolid, ox-oxacillin, p-penicillin, te-tetracycline, qda-quinupristin/dalfopr, tmp/smx-trimethoprim/sulfa, van-vancomycin.

 

- antibiotics not tested or not recommended due to lack of correlation between in vitro results and in vivo activity.

 

All beta lactam antibiotics are automatically reported as resistant on an oxacillin (methicillin) resistant staphylococcus species. Speciation of coagulase negative staphylococcus is only performed when specifically requested by the physician.

 

Comments

·          Penicillin sensitive Streptococcus pneumoniae isolates can be considered sensitive to ampicillin, ampicillin/sulbactam, amoxacill/clavulanic acid, and 1st, 2nd, 3rd, 4th generation cephalosporins.

·          Beta hemolytic Streptococcus species have not demonstrated resistance to penicillin or ampicillin therefore susceptibility testing is not routinely performed. Of the Streptococcus agalactiae performed on isolates recovered from pregnant penicillin allergic women 100% were Penicillin sensitive, 50% were Clindamycin sensitive and 26% were Erythromycin sensitive. Erythromycin resistant strains cannot be reliably interpreted as Clindamycin sensitive without the addition of the “D Test” to test for inducible resistance.

Beginning in 2007 susceptibility testing will be performed by manual Kirby-Bauer Disk Diffusion Method due to a limitation with the Erythromycin/Streptococcus agalactiae anitibioitc/organism combination using the bioMerieux automated identification susceptibility system.

·          Vancomycin resistant Enterococcus species are speciated and the Vancomycin MIC confirmed by alternative methods.